Chemical Constituents and in Vitro/In Vivo Pharmacological Effects of Mentha piperita L. Essential oil in Different Regions of Algeria

Latifa Halli; Lilya Harchaoui; Mohammed Messaoudi; Thoraya Dahmane; Fatiha Aid; Barbara Sawicka; Wafa Zahnit

doi:10.35516/jjps.v18i1.3069

Authors

Latifa Halli Faculty of Biological Sciences, University of Science and Technology Houari Boumediene, Algiers, Algeria. Research and Development Center, SAIDAL GROUP, Algiers, Algeria.
Lilya Harchaoui Faculty of Biological Sciences, University of Science and Technology Houari Boumediene, Algiers, Algeria.
Mohammed Messaoudi Nuclear Research Centre of Birine, Djelfa, Algeria, Ain Oussera, Djelfa, Algeria.
Thoraya Dahmane Department of Agronomic Sciences, University Djillali Bounaama Khemis Miliana, Faculty of Natural and Life Sciences and Earth Sciences, Algeria.
Fatiha Aid Faculty of Biological Sciences, University of Science and Technology Houari Boumediene, Algiers, Algeria.
Barbara Sawicka Department of Plant Production Technology and Commoditties Science, University of Life Sciences in Lublin, Lublin, Akademicka 15 str., Poland.
Wafa Zahnit Department of Chemistry, Faculty of Mathematics and material sciences, Kasdi Merbah University, Laboratory of Valorization and Promotion of Saharan Resources (VPRS), Ouargla, Algeria.

DOI:

https://doi.org/10.35516/jjps.v18i1.3069

Keywords:

Anti-inflammatory, GC/MS, Lamiaceae, Mentha piperita, phytochemical profile, linalool

Abstract

This study focuses on Mentha piperita L. cultivated in two regions with distinct bioclimatic levels. The aim is to assess and compare the yield, chemical composition, and pharmacological activities of the plant in these diverse environmental conditions. The phytochemical profile of Mentha piperita L essential oils was established using gas chromatographic analysis. The pharmacological activities were performed in vivo and in vitro using analgesic, anti-inflammatory, antibacterial and antioxidant assays. The optimal yield of essential oil is obtained from the region of Oued Souf with 1.02% and that of the region of Algiers is equal to 0.86%. The GC/MS analysis revealed a richness of the essential oil in Linalool as well as its derivatives linalyl acetate for Oued Souf and linalyl butyrate for Algiers. In all pharmacological activities, the essential oil of Mentha piperita L from Oued Souf region was significantly more potent than essential oil from Algiers. This study can contribute to the application of Mentha piperita L essential oil in the pharmaceutical industry as a promising natural reservoir of volatile compounds with noteworthy therapeutic properties.

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