تحديد المكونات المهمة صيدلانياً لجذر الكينوا
DOI:
https://doi.org/10.35516/jjps.v16i1.1071الكلمات المفتاحية:
المكونات النشطة بيولوجيًا، تشينوبوديوم كينوا، مستخلص ن-هكسان، تحليل GC-MS، الجذرالملخص
تم إجراء الدراسة الحالية لاستكشاف المركبات النشطة بيولوجيًا من الجزء hexan-n من المستخلص الميثانولي لجذور الكينوا.Chenopodium quinoa Willd). ) لهذا الغرض، تم جمع جذور quinoa .C وتجفيف الظل وسحقها إلى مسحوق ناعم. تم استخلاص مادة المسحوق في ميثانول، وترشيحه، وتم تقسيم المرشح باستخدام hexan-n، متبوعًا بتحليل GC-MS لجزء hexan-n. كشف التحديد الكمي لهذا الجزء عن وجود 15 مكونًا كيميائيًا نباتيًا ذات طبيعة متنوعة. ومن بين هؤلاء octadec-9-enoic acid (44.18٪) ؛ n-hexadecanoic acid (18.87٪) ؛ methyl (Z)-octadec-9-enoate (12.87٪) ؛ methyl hexadecanoate (4.30٪) ؛ 2,3-dihydroxypropyl elaidate (3.63٪) ؛ phthalic acid (3.08٪) ؛ methyl octadecanoate (2.27٪) و 1,12-tridecadiene (2.00٪) باعتبارها الأكثر وفرة للمركبات المتوسطة التكوّن. تم إجراء مسح شامل للأدبيات لجمع المعلومات المتعلقة بالخصائص الصيدلانية للمركبات المحددة. أظهرت بعض المركبات المحددة وهي dodecanoic acid; tetradecanoic acid; 2-benzoyl-d-galactosan; n-hexadecanoic acid; methyl octadecanoate; octadec-9-enoic acid؛ و 2،3-dihydroxypropyl elaidate يمتلكان خصائص مضادة للفطريات، ومضادة للبكتيريا، ومضادة للأكسدة، ومضادة للفيروسات، ومضادة للالتهابات، و / أو مضادة للسرطان.
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