Laryngopharyngeal Reflux Disease in North of Jordan, Prevalence, Awareness and Risk Factors

Authors

  • Hadeel Allan Jordan university of science and technology
  • Yazan Kanaan Jordan University of Science and Technology
  • Ahmad Al Omari Jordan University of Science and Technology https://orcid.org/0000-0002-6531-5164

DOI:

https://doi.org/10.35516/jmj.v59i2.1859

Keywords:

Laryngopharyngeal reflux, Dysphonia, Prevalence, Gastroesophageal reflux

Abstract

Background: laryngopharyngeal reflux (LPR) is the result of retrograde flow of gastric contents to the laryngopharynx, where it comes in contact with tissues of the upper aero-digestive tract.
Aims: We aimed to determine the prevalence and awareness of laryngopharyngeal reflux (LPR) in general population of North Jordan, along with identifying associated risk factors.
Methodology: A cross-sectional study was carried out to determine the prevalence of laryngopharyngeal reflux (LPR) by utilizing the Reflux Symptoms Index (RSI) questionnaire among a randomly chosen group of adult participants. Those scoring ≥13 on the RSI were identified as laryngopharyngeal reflux (LPR) patients, while those scoring <13 were classified as non- laryngopharyngeal reflux (LPR) subjects. The questionnaire was completed by a total of 500 participants, comprising 275 males and 225 females.
Results: The prevalence of LPR in the North Jordanian population was determined to be 28%, with no statistically significant difference observed between genders (p > 0.05). Notably, the age group above 40 years exhibited a higher prevalence rate. Tobacco smoking emerged as the most significant factor associated with LPR. Remarkably, only 1% of participants demonstrated awareness of LPR and its relationship with throat or voice symptoms.
Conclusion: laryngopharyngeal reflux (LPR) was found to be prevalent in 28% of the North Jordanian population, with a strikingly low level of awareness (1%). The study identified tobacco smoking as a prominent risk factor for laryngopharyngeal reflux (LPR). Furthermore, individuals who reported consuming higher amounts of caffeinated beverages displayed a greater incidence of laryngopharyngeal reflux (LPR). However, the study did not examine the relationship between alcohol consumption and LPR due to the absence of alcohol-drinking participants in the sample.

Author Biography

Yazan Kanaan, Jordan University of Science and Technology

 

  • Yazan Kanaan: Department of Special Surgery, Division of Otolaryngology, Faculty of Medicine, Jordan University of Science and Technology, P O Box 3030, Irbid 22110.

References

Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of therole of acid and pepsin in the development of laryngeal injury. Laryngoscope. 1991; 101(4 pt 2 suppl 53): 1-78. 2. Postma GN, Tomek MS, Belafsky PC, Koufman JA. Esophageal motor function in laryngopharyngealreflux is superior to that of classic gastroesophageal reflux disease. Ann Otol RhinolLaryngol 2001; 110(12): 1114–1116.

Shaker R, Dodds WJ, Ren J, Hogan WJ, Arndorfer RC. Oesophagoglottal closure reflux: A mechanism of airway protection. Gastroenterology 1992; 102(3): 857–61.

Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI). J Voice. 2002 Jun; 16(2): 274-7.

doi: 10.1016/s0892-1997(02)00097-8. PMID: 12150380.

Habermann W, Schmid C, Neumann K, DeVaney T, Hammer H. Refluxsymptom index and reflux finding score in otolaryngologic practice. J Voice. 2012; 26(3): e123–7.

Lechien JR, Saussez S, Muls V, Barillari MR, Chiesa-Estomba CM, Hans S, Karkos PD. Laryngopharyngeal Reflux: A State-of-the-Art Algorithm Management for Primary Care Physicians. Journal of Clinical Medicine. 2020; 9(11): 3618. https: //doi.org/10.3390/jcm9113618

Martinucci I, de Bortoli N, Savarino E, et al. Optimal treatment of laryngopharyngeal reflux disease. Ther Adv Chronic Dis. 2013; 4(6): 287-301. doi: 10.1177/2040622313503485

Review article: reflux and its consequences--the laryngeal, pulmonary and oesophageal manifestations. Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP) Kingston-upon-Hull, UK, 21-23 April 2010.

Belafsky PC, Postma GN, Koufman JA. The validity and reliability of the reflux finding score (RFS). Laryngoscope. 2001 : 8: 111(8): 1313-7. doi: 10.1097/00005537-200108000-00001. PMID: 11568561.

Laryngopharyngeal Reflux Disease in North of Jordan … Allan et al.

Noordzij, J Pieter et al. “Correlation of pH probe-measured laryngopharyngeal reflux with symptoms and signs of reflux laryngitis.” The Laryngoscope vol. 112,12 (2002): 2192-5. doi: 10.1097/00005537-200212000-00013

Samuels, T. L., & Johnston, N. (2010). Pepsin as a Marker of Extraesophageal Reflux. Annals of Otology, Rhinology & Laryngology, 119(3), 203–208.

https: //doi.org/10.1177/000348941011900310 12. Wood JM, Hussey DJ, Woods CM, Watson DI, Carney AS. Biomarkers and laryngopharyngeal reflux. J Laryngol Otol. 2011: 12: 125(12): 1218-24. doi: 10.1017/S0022215111002234. Epub 2011 Sep 14. PMID: 21914248. 13. Campagnolo AM, Priston J, Thoen RH, Medeiros T, Assunção AR. Laryngopharyngeal reflux: diagnosis, treatment, and latest research. Int Arch Otorhinolaryngol. 2014; 18(2): 184-191. doi: 10.1055/s-0033-1352504

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Published

2025-04-27

How to Cite

Allan, H., Kanaan, Y. ., & Al Omari, A. (2025). Laryngopharyngeal Reflux Disease in North of Jordan, Prevalence, Awareness and Risk Factors. Jordan Medical Journal, 59(2). https://doi.org/10.35516/jmj.v59i2.1859

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