The Relationship between Diabetic Patients' Health Literacy and HBA1c Level in Jordan

Authors

  • Abdel Qader Al Bawab Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • Walid Al-Qerem Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • Anan Jarab College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan
  • Judith Eberhardt Department of Psychology, School of Social Sciences, Humanities and Law, Teesside University, Borough Road, Middlesbrough TS1 3BX, UK
  • Fawaz Alasmari Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh , Saudi Arabia
  • Alaa Hammad Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • Safa Alkaee Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • Zein Alsabaa Department of Pharmacy, Faculty of Pharmacy, Petra University, Amman, Jordan

DOI:

https://doi.org/10.35516/jjps.v18i3.2821

Keywords:

Health literacy, Diabetes Miletus, Jordan, HBA1c, glycemic control

Abstract

Objective: This study aimed to explore how diabetic health literacy influences glycated hemoglobin HbA1c levels—a crucial marker of long-term blood sugar control—in Jordanian patients with type 2 diabetes.

Methods: Over a four-month period at a major public hospital in Amman, we enrolled 400 patients with type 2 diabetes mellitus in this cross-sectional study. The study used the Jordanian Diabetic Health Literacy Questionnaire (JDHLQ). This validated tool assesses health literacy among Arabic-speaking individuals.

Results: The findings revealed a significant link between higher health literacy scores and lower HbA1c levels. Specifically, each additional point on the JDHLQ was associated with a 0.040 decrease in HbA1c (95% CI [-0.078, -0.003], p=0.035). Patients taking more medications and those without insurance also had significantly higher HbA1c levels.

Conclusion: These results highlight the vital role of health literacy in managing diabetes effectively and support the implementation of targeted educational programs to improve patient outcomes in Jordan. The study emphasizes the need for policy improvements in diabetes care.

Practice Implications:  Understanding the key factors that influence disease control in type 2 diabetes patients—including the impact of health literacy—is essential for developing targeted interventions, enhancing patient outcomes, and reducing the strain of diabetes on the healthcare system.

References

Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010; 33:S62-S69.

https://doi.org/10.2337/dc10-S062 DOI: https://doi.org/10.2337/dc10-S062

Khan H.H., Khan F.U., Ahmad T., Guo H., Shi B. Evaluation of health-related quality of life in patients with type 2 diabetes mellitus through EQ-5D-3L in public sector hospitals of Quetta, Pakistan. Jordan J. Pharm. Sci. 2025; 18:410-422.

https://doi.org/10.35516/JJPS.V18I2.2614 DOI: https://doi.org/10.35516/jjps.v18i2.2614

Ahmad M.N., Farah A.I., Al-Qirim T.M. The cardiovascular complications of diabetes: a striking link through protein glycation. Rom. J. Intern. Med. 2020; 58:188-198. https://doi.org/10.2478/RJIM-2020-0021 DOI: https://doi.org/10.2478/rjim-2020-0021

Tomic D., Shaw J.E., Magliano D.J. The burden and risks of emerging complications of diabetes mellitus. Nat. Rev. Endocrinol. 2022; 18:525-539.

https://doi.org/10.1038/s41574-022-00690-7 DOI: https://doi.org/10.1038/s41574-022-00690-7

Ajlouni K., Batieha A., Jaddou H., Khader Y., Abdo N., El-Khateeb M., Hyassat D., Al-Louzi D. Time trends in diabetes mellitus in Jordan between 1994 and 2017. Diabet. Med. 2019; 36:1176-1182.

https://doi.org/10.1111/dme.13894 DOI: https://doi.org/10.1111/dme.13894

Bin Siddique M.K., Islam S.M.S., Banik P.C., Rawal L.B. Diabetes knowledge and utilization of healthcare services among patients with type 2 diabetes mellitus in Dhaka, Bangladesh. BMC Health Serv. Res. 2017; 17:586. https://doi.org/10.1186/s12913-017-2542-3 DOI: https://doi.org/10.1186/s12913-017-2542-3

Shaw J.E., Sicree R.A., Zimmet P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 2010; 87:4-14. https://doi.org/10.1016/j.diabres.2009.10.007 DOI: https://doi.org/10.1016/j.diabres.2009.10.007

Chen G.-D., Huang C.-N., Yang Y.-S., Lew-Ting C.-Y. Patient perception of understanding health education and instructions has moderating effect on glycemic control. BMC Public Health. 2014; 14:683. https://doi.org/10.1186/1471-2458-14-683 DOI: https://doi.org/10.1186/1471-2458-14-683

Lee E.-H., Lee Y.W., Lee K.-W., Nam M., Kim S.H. A new comprehensive diabetes health literacy scale: development and psychometric evaluation. Int. J. Nurs. Stud. 2018; 88:1-8.

https://doi.org/10.1016/j.ijnurstu.2018.08.002 DOI: https://doi.org/10.1016/j.ijnurstu.2018.08.002

Tefera Y.G., Gebresillassie B.M., Emiru Y.K., Yilma R., Hafiz F., Akalu H., Ayele A.A. Diabetic health literacy and its association with glycemic control among adult patients with type 2 diabetes mellitus attending the outpatient clinic of a university hospital in Ethiopia. PLoS One. 2020; 15:e0231291.

https://doi.org/10.1371/journal.pone.0231291

Schillinger D. Association of health literacy with diabetes outcomes. JAMA. 2002; 288:475. https://doi.org/10.1001/jama.288.4.475 DOI: https://doi.org/10.1001/jama.288.4.475

Bin Rakhis S.A., AlDuwayhis N.M., Aleid N., AlBarrak A.N., Aloraini A.A. Glycemic control for type 2 diabetes mellitus patients: a systematic review. Cureus. 2022. https://doi.org/10.7759/cureus.26180 DOI: https://doi.org/10.7759/cureus.26180

Almomani M.H., Al-Tawalbeh S. Glycemic control and its relationship with diabetes self-care behaviors among patients with type 2 diabetes in northern Jordan: a cross-sectional study. Patient Prefer. Adherence. 2022; 16:449-465. https://doi.org/10.2147/PPA.S343214 DOI: https://doi.org/10.2147/PPA.S343214

Al-Taani G.M., Muflih S.M., Alsharedeh R., Karasneh R., Al-Azzam S.I. Impact of COVID-19 pandemic on the mental health of diabetic patients in Jordan: an online survey. Jordan J. Pharm. Sci. 2024; 17:717-729.

https://doi.org/10.35516/JJPS.V17I4.2234 DOI: https://doi.org/10.35516/jjps.v17i4.2234

Khattab M., Khader Y.S., Al-Khawaldeh A., Ajlouni K. Factors associated with poor glycemic control among patients with type 2 diabetes. J. Diabetes Complicat. 2010; 24:84-89. https://doi.org/10.1016/j.jdiacomp.2008.12.008 DOI: https://doi.org/10.1016/j.jdiacomp.2008.12.008

Sonji N.M., Sonji G.M. Fostering healthier choices: empowering pharmacy students to bridge the food label gap in Lebanon. Jordan J. Pharm. Sci. 2024; 17:582-593. https://doi.org/10.35516/JJPS.V17I3.2290 DOI: https://doi.org/10.35516/jjps.v17i3.2290

Wan E.Y.F., Yu E.Y.T., Mak I.L., Youn H.M., Chan K.S., Chan E.W.Y., Wong I.C.K., Lam C.L.K. Diabetes with poor-control HbA1c is cardiovascular disease ‘risk equivalent’ for mortality: UK Biobank and Hong Kong population-based cohort study. BMJ Open Diabetes Res. Care. 2023; 11:e003075. https://doi.org/10.1136/bmjdrc-2022-003075 DOI: https://doi.org/10.1136/bmjdrc-2022-003075

Sherwani S.I., Khan H.A., Ekhzaimy A., Masood A., Sakharkar M.K. Significance of HbA1c test in diagnosis and prognosis of diabetic patients. Biomark Insights. 2016; 11:BMI.S38440.

https://doi.org/10.4137/BMI.S38440 DOI: https://doi.org/10.4137/BMI.S38440

Rani P.K., Raman R., Subramani S., Perumal G., Kumaramanickavel G., Sharma T. Knowledge of diabetes and diabetic retinopathy among rural populations in India, and the influence of knowledge of diabetic retinopathy on attitude and practice. Rural Remote Health. 2008; 8:838. DOI: https://doi.org/10.22605/RRH838

Powers M.A., Bardsley J., Cypress M., Duker P., Funnell M.M., Fischl A.H., Maryniuk M.D., Siminerio L., Vivian E. Diabetes self-management education and support in type 2 diabetes. Diabetes Educ. 2017; 43:40-53. https://doi.org/10.1177/0145721716689694 DOI: https://doi.org/10.1177/0145721716689694

Al-Qerem W., Jarab A., Eberhardt J., Alasmari F., Alkaee S.M., Alsabaa Z.H. Development and validation of the Jordanian diabetic health literacy questionnaire: enhancing diabetes management in Arabic-speaking populations. Healthcare. 2024; 12:0801. https://doi.org/10.3390/healthcare12070801 DOI: https://doi.org/10.3390/healthcare12070801

Al-Qerem W., Al Bawab A.Q., Abusara O., Alkhatib N., Horne R. Validation of the Arabic version of medication adherence report scale questionnaire and beliefs about medication-specific questionnaire: a factor analysis study. PLoS One. 2022; 17:e0266606. DOI: https://doi.org/10.1371/journal.pone.0266606

Green S.B. How many subjects does it take to do a regression analysis. Multivar. Behav. Res. 1991; 26:499-510. https://doi.org/10.1207/S15327906MBR2603_7 DOI: https://doi.org/10.1207/s15327906mbr2603_7

Aung W.P., Htet A.S., Bjertness E., Stigum H., Chongsuvivatwong V., Kjøllesdal M.K.R. Urban–rural differences in the prevalence of diabetes mellitus among 25–74 year-old adults of the Yangon Region, Myanmar: two cross-sectional studies. BMJ Open. 2018; 8:e020406. https://doi.org/10.1136/bmjopen-2017-020406 DOI: https://doi.org/10.1136/bmjopen-2017-020406

Al-Qerem W., Jarab A.S., Badinjki M., Hammad A., Ling J., Alasmari F. Factors associated with glycemic control among patients with type 2 diabetes: a cross-sectional study. Eur. Rev. Med. Pharmacol. Sci. 2022; 26:2415-2421. https://doi.org/10.26355/EURREV_202204_28475

Tefera Y.G., Gebresillassie B.M., Emiru Y.K., Yilma R., Hafiz F., Akalu H., Ayele A.A. Diabetic health literacy and its association with glycemic control among adult patients with type 2 diabetes mellitus attending the outpatient clinic of a university hospital in Ethiopia. PLoS One. 2020; 15:e0231291.

https://doi.org/10.1371/journal.pone.0231291 DOI: https://doi.org/10.1371/journal.pone.0231291

AlSharit B.A., Alhalal E.A. Effects of health literacy on type 2 diabetic patients’ glycemic control, self-management, and quality of life. Saudi Med. J. 2022; 43:465-472. https://doi.org/10.15537/smj.2022.43.5.20210917 DOI: https://doi.org/10.15537/smj.2022.43.5.20210917

Olesen K., Willaing I., Maindal H.T., Andersen G.S. Does health literacy predict cardiometabolic marker trajectories among people with diabetes? A longitudinal mixed-effect analysis. J. Diabetes Complicat. 2023; 37:108358. https://doi.org/10.1016/j.jdiacomp.2022.108358. DOI: https://doi.org/10.1016/j.jdiacomp.2022.108358

Jang G.Y., Chang S.J., Noh J.H. Relationships among health literacy, self-efficacy, self-management, and HbA1c levels in older adults with diabetes in South Korea: a cross-sectional study. J. Multidiscip. Healthc. 2024; 17:409-418.

https://doi.org/10.2147/JMDH.S448056 DOI: https://doi.org/10.2147/JMDH.S448056

Butayeva J., Ratan Z.A., Downie S., Hosseinzadeh H. The impact of health literacy interventions on glycemic control and self-management outcomes among type 2 diabetes mellitus: a systematic review. J. Diabetes. 2023; 15:724-735. https://doi.org/10.1111/1753-0407.13436 DOI: https://doi.org/10.1111/1753-0407.13436

Brož J., Janíčková Ždárská D., Štěpánová R., Kvapil M. Addition of basal insulin to oral antidiabetic agents in patients with inadequately controlled type 2 diabetes leads to improved HbA1c levels: metabolic control, frequency of hypoglycemia, and insulin titration analysis as results of a prospective observational study (BALI Study). Diabetes Ther. 2019; 10:663-672. https://doi.org/10.1007/s13300-019-0584-8 DOI: https://doi.org/10.1007/s13300-019-0584-8

Lavernia F., Adkins S.E., Shubrook J.H. Use of oral combination therapy for type 2 diabetes in primary care: meeting individualized patient goals. Postgrad. Med. 2015; 127:808-817.

https://doi.org/10.1080/00325481.2015.1085293 DOI: https://doi.org/10.1080/00325481.2015.1085293

Polonsky W., Henry R. Poor medication adherence in type 2 diabetes: recognizing the scope of the problem and its key contributors. Patient Prefer. Adherence. 2016; 10:1299-1307. https://doi.org/10.2147/PPA.S106821 DOI: https://doi.org/10.2147/PPA.S106821

Sarbacker G.B., Urteaga E.M. Adherence to insulin therapy. Diabetes Spectr. 2016; 29:166-170. https://doi.org/10.2337/diaspect.29.3.166

Alsaidan A.A., Alsaidan O.A., Mallhi T.H., Khan Y.H., Alzarea A.I., Alanazi A.S. Assessment of adherence to insulin injections among diabetic patients on basal-bolus regimen in primary and secondary healthcare centers in Al-Jouf Region of Saudi Arabia: a descriptive analysis. J. Clin. Med. 2023; 12:3474. https://doi.org/10.3390/jcm12103474 DOI: https://doi.org/10.3390/jcm12103474

Sarbacker G.B., Urteaga E.M. Adherence to insulin therapy. Diabetes Spectr. 2016; 29:166-170. https://doi.org/10.2337/diaspect.29.3.166 DOI: https://doi.org/10.2337/diaspect.29.3.166

Jannoo Z., Mamode Khan N. Medication adherence and diabetes self-care activities among patients with type 2 diabetes mellitus. Value Health Reg. Issues. 2019; 18:30-35. https://doi.org/10.1016/j.vhri.2018.06.003 DOI: https://doi.org/10.1016/j.vhri.2018.06.003

Bowker S.L. Lack of insurance coverage for testing supplies is associated with poorer glycemic control in patients with type 2 diabetes. Can. Med. Assoc. J. 2004; 171:39-43. https://doi.org/10.1503/cmaj.1031830. DOI: https://doi.org/10.1503/cmaj.1031830

Kelly C., Nguyen H., Liu J., Chapman K.S.M., Peter M., Leon C., Laferriere K., Ravelson J., Wolf W. Unique associations between health insurance and HbA1c in adults with type 1 diabetes. Diabetes. 2022; 71:629-P. https://doi.org/10.2337/db22-629-P. DOI: https://doi.org/10.2337/db22-629-P

Downloads

Published

2025-09-24

How to Cite

Al Bawab, . A. Q., Al-Qerem, W., Jarab, A., Eberhardt, J., Alasmari, F., Hammad, A., Alkaee, S., & Alsabaa, Z. (2025). The Relationship between Diabetic Patients’ Health Literacy and HBA1c Level in Jordan. Jordan Journal of Pharmaceutical Sciences, 18(3), 748–758. https://doi.org/10.35516/jjps.v18i3.2821

Issue

Section

Articles

Most read articles by the same author(s)