Therapeutic Potential of Traditional Medicinal Plants from the Central Algerian Steppe for Treating Common Digestive Disorders
DOI:
https://doi.org/10.35516/jjps.v18i3.3155Keywords:
Therapeutic potential, digestive disorders, medicinal plants, central Algerian steppe, traditional medicineAbstract
In the central Algerian steppe, digestive system disorders are a common affliction that the majority of the population treats using medicinal plants. This study aims to evaluate the therapeutic potential of the medicinal plants used for treating four common disorders: colopathy, gastric ulcers, acute diarrhea, and chronic constipation. To achieve this, a survey was conducted using a semi-structured questionnaire, involving a total of 75 traditional phytotherapy practitioners. The questionnaire comprised two sections: socio-demographic information about the practitioners and details regarding the cited plants. Data were collected through field survey forms, categorizing participants by gender, age, education level, and professional experience. Detailed botanical information about the identified plants was carefully collected and analyzed. The diversity of medicinal plants used for digestive disorders was inventoried and assessed using adequate statistics. The survey identified 57 plant species across 32 botanical families, with a predominance of Lamiaceae (9 species) and Asteraceae (7 species). Infusion was the most common preparation method (44%) followed by decoction (38%). These findings emphasize the importance of medicinal plants in traditional treatment of gastric disorders in the region and provide a foundation for future studies on their biological and chemical potentials. The study identified a wide variety of medicinal plants used to treat conditions such as colopathy, gastric ulcers, acute diarrhea, and chronic constipation, with key plants like Cuminum cyminum, Teucrium polium, Artemisia campestris, and Senna alexandrina noted for their high efficacy. The use of single plants (8 species) for multiple disorders was observed, reflecting the interconnected nature of these conditions and the broad medicinal properties of the plants. This investigation underscores the extensive traditional knowledge and rich diversity of medicinal plants used in the central Algerian steppe for treating digestive disorders. The findings highlight the importance of these plants and suggest potential areas for further pharmacological research to validate their efficacy and safety.
References
Bahassan A., Zidane L., El Yacoubi H., Rochdi A. Ethnobotanique et taxonomie des plantes médicinales utilisées pour le traitement des pathologies du système digestif à Hadramaout (Yémen). Phytother. 2014; 12:399-416. DOI: https://doi.org/10.1007/s10298-014-0897-8
Barroso W., Duarte Gondim R., Marques V., Lael M., Santos P., Oliveira Castro A. Pharmacognostic Characterization of Laurus nobilis L. Leaves. J. Chem. Pharm. Res. 2018; 10:30-7.
Habib N., Regagba Z., Miara M. D., Hammou M. A., Snorek J. Floristic diversity of steppe vegetation in the region of Djelfa, North-West Algeria. Acta Bot. Malacit. 2020; 45:37-46. DOI: https://doi.org/10.24310/abm.v45i.7987
Taibaoui B., Douaoui A., Bouxin G. Florist diversity of the southern Algerian steppe: case of the Djelfa region (Algeria). Lejeunia Rev. Bot. 2020; 203:1-41.
Tangjitman K., Wongsawad C., Kamwong K., Sukkho T., Trisonthi C. Ethnomedicinal plants used for digestive system disorders by the Karen of northern Thailand. J. Ethnobiol. Ethnomed. 2015; 11:1-13. DOI: https://doi.org/10.1186/s13002-015-0011-9
Black C. J., Drossman D. A., Talley N. J., Ruddy J., Ford A. C. Functional gastrointestinal disorders: advances in understanding and management. Lancet. 2020; 396:1664-74. DOI: https://doi.org/10.1016/S0140-6736(20)32115-2
Es-Safi I., Mechchate H., Amaghnouje A., Jawhari F. Z., Bari A., Cerruti P., Bousta D. Medicinal plants used to treat acute digestive system problems in the region of Fez-Meknes in Morocco: An ethnopharmacological survey. Ethnobot. Res. Appl. 2020; 20:1-14. DOI: https://doi.org/10.32859/era.20.25.1-14
Bammou M., Elbouny H., El Finou H., Ouahzizi B., Sellam K., Nassiri L., Bouhlali E. D. T. Ethnobotanical survey of medicinal plants claimed by traditional herbal practitioners to manage digestive disorders in an oasis of Tafilalet-Morocco. Plant Sci. Today. 2024; 11:10–20. DOI: https://doi.org/10.14719/pst.3357
Mikou K., Rachiq S., Jarrar O. A. Ethnobotanical survey of medicinal and aromatic plants used by the people of Fez in Morocco. Phytothérapie. 2016; 14:35-43. DOI: https://doi.org/10.1007/s10298-015-1013-4
Redouan F. Z., Yebouk C., Crisafulli A., Picone R. M., Merzouki A. Ethnopharmacological preparations used for digestive system disorders in Talassemtane National Park (North of Morocco). Ethnobot. Res. Appl. 2022; 24:1-25. DOI: https://doi.org/10.32859/era.24.2.1-25
Cheema H. S., Singh M. P. The use of medicinal plants in digestive system related disorders—a systematic review. Ayurved Herb. Med. 2021; 7:182-7. DOI: https://doi.org/10.31254/jahm.2021.7303
Ali Boutlelis D., Sabrina C., Mounia B., Salah B., Ibtissam L., Chaima B. Therapeutic potential of traditional medicinal plants from Algeria for treatment of liver diseases. Jordan J. Pharm. Sci. 2023; 16:529-40. DOI: https://doi.org/10.35516/jjps.v16i3.685
Belmouhoub M., Boubekeur A., Tacherfiout M., Boukhalfa F., Khaled Khodja Y., Bachir-bey M. Ethnobotanical survey of medicinal plants used by people cured of SARS-CoV-2 in the center of Algeria. Ethnobot. Res. Appl. 2024; 28:1-26. DOI: https://doi.org/10.32859/era.28.42.1-26
Issa R., Khattabi A., Alkarem T., Altameemi O. The use of antidiabetic herbal remedies by Jordanian herbalist: A comparison of folkloric practice vs. evidence-based pharmacology. Jordan J. Pharm. Sci. 2019; 12:23-37.
Kesh L. Functional gastrointestinal disorders: Insights into diagnosis and treatment strategies. Arch. Gen. Intern. Med. 2024; 8:219.
Wang R., Li Z., Liu S., Zhang D. Global, regional, and national burden of 10 digestive diseases in 204 countries and territories from 1990 to 2019. Front. Public Health. 2023; 11:1061453. DOI: https://doi.org/10.3389/fpubh.2023.1061453
El Heddi S., Benrima A. Biodiversité acridienne et floristique en milieux steppiques naturels et reboisés dans la région de Moudjbara-Djelfa (Algérie). Rev. Agrobiol. 2017; 7:321-33.
Yabrir B., Laoun A., Chenouf N. S., Mati A. Caractéristiques des élevages ovins de la steppe centrale de l’Algérie en relation avec l’aridité du milieu: cas de la wilaya de Djelfa. Livest. Res. Rural Dev. 2015; 27:1-23.
Tardío J., Pardo-de-Santayana M. Cultural importance indices: a comparative analysis based on the useful wild plants of Southern Cantabria (Northern Spain). Econ. Bot. 2008; 62:24-39. DOI: https://doi.org/10.1007/s12231-007-9004-5
Umair M., Altaf M., Abbasi A. M. An ethnobotanical survey of indigenous medicinal plants in Hafizabad district, Punjab-Pakistan. PloS One. 2017; 12:e0177912. DOI: https://doi.org/10.1371/journal.pone.0177912
Idm'hand E., Msanda F., Cherifi K. Ethnobotanical survey of medicinal plants used in treatment of kidney stones in Tarfaya province (Morocco). Int. J. Innov. Appl. Stud. 2019; 26:711-9.
Sarri M., Mouyet F. Z., Benziane M., Cheriet A. Traditional use of medicinal plants in a city at steppic character (M’sila, Algeria). J. Pharm. Pharmacogn. Res. 2014; 2:31-5. DOI: https://doi.org/10.56499/jppres14.019_2.2.31
Rehman S., Iqbal Z., Qureshi R., Shah G. M., Afzal A., Rahman K. U., Hussain W., Younas M., Latif S., Siddiqa A. Quantitative ethnomedicinal survey of wild edible fruits used by the indigenous community in North Waziristan, Khyber Pakhtunkhwa, Pakistan. Ethnobot. Res. Appl. 2024; 28:1-20. DOI: https://doi.org/10.32859/era.28.13.1-20
Redouan F. Z., Benítez G., Picone R. M., Crisafulli A., Yebouk C., Bouhbal M., Merzouki A. Traditional medicinal knowledge of apiaceae at Talassemtane National Park (northern Morocco). S. Afr. J. Bot. 2020; 131:118-30. DOI: https://doi.org/10.1016/j.sajb.2020.02.004
Orch H., Chaachouay N., Douiri E. M., Faiz N., Zidane L., Douira A. Use of medicinal plants in dermato-cosmetology: An ethnobotanical study among the population of Izarène. Jordan J. Pharm. Sci. 2021; 14:23-340.
Alaoui A., Laaribya S. Etude ethnobotanique et floristique dans les communes rurales Sehoul et Sidi-Abderrazak (cas de la Maamora-Maroc Septentrional). Nat. Technol. 2017.
Belhaj S., Zidane L. Ethnobotanical and ethnopharmacological study of medicinal plants used for the treatment of diseases of the digestive tract in the High Atlas Central of Morocco (North Africa). J. Anal Sci. Appl. Biotechnol. 2021; 3:7-14.
Ahmed J. T., Alibraheem S., Taresh F. J., Mhalhal S. L. Evaluate the anti-ulcer activity of pomegranate peel powder (Punica granatum) in local rabbits infected by aspirin-induced peptic ulcer. Int. J. Pharm. Res. 2020; 12:2980-7. DOI: https://doi.org/10.31838/ijpr/2020.12.03.422
Layadi I., Laiche A. T., Tlili M. L. Medicinal plants used by traditional healers in the treatment of gastrointestinal disorders in Oued Souf region (southeast of Algeria). Jordan J. Pharm. Sci. 2024; 17:225-41. DOI: https://doi.org/10.35516/jjps.v17i2.1783
Dey A. K., Rashid M. M. O., Millat M. S., Rashid M. M. Ethnobotanical survey of medicinal plants used by traditional health practitioners and indigenous people in different districts of Chittagong division, Bangladesh. Int. J. Pharm. Pharm. Sci. 2014; 3:1-7.
Das G., Das S., Talukdar A., Venil C., Bose S., Banerjee S., Shin H.-S., Gutierrez-Grijalva E., Heredia J., Patra J. Pharmacology and ethnomedicinal potential of selected plants species from Apiaceae (Umbelliferae). Comb. Chem. High. Throughput. Screen. 2023; 26:256-88. DOI: https://doi.org/10.2174/1386207325666220406110404
Sarkar M., Chawla P.,:In: Herbs, spices, and medicinal plants for human gastrointestinal disorders.Goyal, M. R., Birwal P. C. and Durgesh N. (Eds).; Apple Academic Press, 2022; Chapter 9, pp 125-140. DOI: https://doi.org/10.1201/9781003189749-11
Brahmi F., Khaled-Khodja N., Bezeghouche R., Bouharis S., Elsebai M. F., Madani K., Boulekbache-Makhlouf L. Ethnobotanical study of the most lamiaceae used as medicinal and culinary plants by the population of Bejaia province, Algeria. Jordan J. Pharm. Sci. 2023; 16:268-81. DOI: https://doi.org/10.35516/jjps.v16i2.1330
Mehrabani D., Rezaee A., Azarpira N., Fattahi M. R., Amini M., Tanideh N., Panjehshahin M. R., Saberi-Firouzi M. The healing effects of Teucrium polium in the repair of indomethacin-induced gastric ulcer in rats. Saudi Med. J. 2009; 30:494-9.
Al-Howiriny T., Alsheikh A., Alqasoumi S., Al-Yahya M., ElTahir K., Rafatullah S. Protective Effect of Origanum majorana L.'Marjoram'on various models of gastric mucosal injury in rats. Am. J. Chin. Med. 2009; 37:531-45. DOI: https://doi.org/10.1142/S0192415X0900703X
Rolnik A., Olas B. The plants of the Asteraceae family as agents in the protection of human health. Int. J. Mol. Sci. 2021; 22:3009. DOI: https://doi.org/10.3390/ijms22063009
Meriem A., Msaada K., Sebai E., Aidi Wannes W., Salah Abbassi M., Akkari H. Antioxidant, anthelmintic and antibacterial activities of red juniper (Juniperus phoenicea L.) essential oil. J. Essent. Oil Res. 2022; 34:163-72. DOI: https://doi.org/10.1080/10412905.2021.1941338
Ezzat S. M., Ezzat M. I., Okba M. M., Menze E. T., Abdel-Naim A. B. The hidden mechanism beyond ginger (Zingiber officinale Rosc.) potent in vivo and in vitro anti-inflammatory activity. J. Ethnopharmacol. 2018; 214:113-23. DOI: https://doi.org/10.1016/j.jep.2017.12.019
Ajayi C. O., Funso-Babarimisa F., Elujoba A. A. Laxative activities of Cassia sieberiana and Senna obtusifolia. Afr. J. Tradit. Complement Altern. Med. 2014; 11:44-7. DOI: https://doi.org/10.4314/ajtcam.v11i4.7
Ramchander P. J., Jalwal P., Middha A. Recent advances on senna as a laxative: a comprehensive review. J. Pharmacogn. Phytochem. 2017; 6:349-53.
Jena J., Gupta A. K. Ricinus communis Linn: a phytopharmacological review. Int. J. Pharm. Pharm. Sci. 2012; 4:25-9.
Picon P. D., Picon R. V., Costa A. F., Sander G. B., Amaral K. M., Aboy A. L., Henriques A. T. Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation. BMC Complement. Altern. Med. 2010; 10:1-9. DOI: https://doi.org/10.1186/1472-6882-10-17
Adnan M., Bibi R., Azizullah A., Andaleeb R., Mussarat S., Tariq A., Ullah R., Elsalam N., Khan A. L., Begum S. Ethnomedicinal plants used against common digestive problems. Afr. J. Tradit. Complement Altern. Med. 2015; 12:99-117. DOI: https://doi.org/10.21010/ajtcam.v12i5.15
Muhammad Ishtiaq M. I., Mehvish Maqbool M. M., Tanveer Hussain T. H. Interrelationship of cultural diversity and biodiversity and its impact on conservation. Pak. J. Bot. 2012; 44:245-56.
Allaq A. A., Sidik N. J., Abdul-Aziz A., Ahmed I. A. Cumin (Cuminum cyminum L.): A review of its ethnopharmacology, phytochemistry. Biomed. Res. Ther. 2020; 7:4016-21. DOI: https://doi.org/10.15419/bmrat.v7i9.634
Ghoshegir S. A., Mazaheri M., Ghannadi A., Feizi A., Babaeian M., Tanhaee M., Karimi M., Adibi P. Pimpinella anisum in the treatment of functional dyspepsia: A double-blind, randomized clinical trial. J. Res. Med. Sci. 2015; 20:13-21.
Fawzi M., Kamel Z., Farhan S. Anti-inflammatory effect of sage (Salvia officinalis) extracts abstract on oral health. Iraqi. Dent. J. 2017; 39:1-6. DOI: https://doi.org/10.26477/idj.v39i1.111
Algandaby M. M. Healing activity of a muco-adhesive formula of Teucrium polium against acetic acid-induced oral ulcer in rats. J. King. Saud. Univ. Sci. 2024; 36:103251. DOI: https://doi.org/10.1016/j.jksus.2024.103251
Ben Ali M. J., Guesmi F., Harrath A. H., Alwasel S., Hedfi A., Ncib S., Landoulsi A., Aldahmash B., Ben-Attia M. Investigation of antiulcer and antioxidant activity of Juniperus phoenicea L. (1753) essential oil in an experimental rat model. Biol. Pharm. Bull. 2015; 38:1738-46. DOI: https://doi.org/10.1248/bpb.b15-00412
Chauhan I., Sharma A., Gangwar M., Gautam M. K., Singh A., Goel R. K. Gastric antiulcer and ulcer healing effects of Punica granatum L. peel extract in rats: Role of offensive and defensive mucosal factors and oxidative stress. Int. J. Pharm. Pharm. Sci. 2013; 9:6-11. DOI: https://doi.org/10.22159/ijpps.2017v9i5.9851
Megdiche-Ksouri W., Trabelsi N., Mkadmini K., Bourgou S., Noumi A., Snoussi M., Barbria R., Tebourbi O., Ksouri R. Artemisia campestris phenolic compounds have antioxidant and antimicrobial activity. Ind. Crops Prod. 2015; 63:104-13. DOI: https://doi.org/10.1016/j.indcrop.2014.10.029
Marghich M., Amrani O., Makrane H., Aziz M. Antidiarrheal activity of aqueous extract of Artemisia campestris L. subsp. Glutinosa. Trop. J. Nat. Prod. Res. 2021; 5:1246-9. DOI: https://doi.org/10.26538/tjnpr/v5i7.14
Kayande N., Kushwah P., Vir D. Evaluation of anti diarrheal potential of cinnamon leaves. PharmaTutor. 2014; 2:124-7.
Akbar S. In Handbook of 200 medicinal plants: A comprehensive review of their traditional medical uses and scientific justifications. Akbar S. (Ed).; Springer International Publishing, Cham, 2020; pp 1629-1637. DOI: https://doi.org/10.1007/978-3-030-16807-0
Tungmunnithum D., Thongboonyou A., Pholboon A., Yangsabai A. Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: An overview. Medicines. 2018; 5:93. DOI: https://doi.org/10.3390/medicines5030093
Kattuoa M., Issa R., Beitawi S. Commonly used herbal remedies for the treatment of primary dysmenorrhea and Heavy menstrual bleeding by herbalists in Amman, Jordan: A cross-sectional survey. Jordan J. Pharm. Sci. 2020; 13:467-83.
Kaur A. P., Sonali B., Daljeet S. D., Eugenie N., Natália C.-M., Kamil K., Chirag C., Reena S., Harsh K., Fatih Ș., Kumar V., Verma R., Kumar D. Plant prebiotics and their role in the amelioration of diseases. Biomolecules. 2021; 11:440. DOI: https://doi.org/10.3390/biom11030440
Barmak M. J., Mahmoudi R., Bardania H. Evaluation of the effect of the internal layer of oak fruit (jaft) extract on the prevention of gastric ulcers caused by stress in male rats. J. Med. Life. 2018; 11:225. DOI: https://doi.org/10.25122/jml-2017-0025







