Clinical Trials on Intermittent Fasting Effects on Health and Diseases published from January 2022 to January 2024: A literature review
DOI:
https://doi.org/10.35516/jmj.v60i1.3401الكلمات المفتاحية:
Intermittent Fasting، Health، healthالملخص
Background: Intermittent fasting (IF) encompasses a variety of dietary methodologies, featuring well-recognized approaches such as the 16/8 or 5:2 diets, or alternate-day fasting (ADF), alongside various other regimens consisting mainly of alternate periods of fasting and eating. It has gained significant attention in recent years for its potential health benefits. This literature review explores the effects of intermittent fasting on health and diseases based on clinical trials published from January 2022 to January 2024.
Objective: Through a critical appraisal of recent clinical trials, this review aims to provide insights into the efficacy, safety, and mechanisms underlying intermittent fasting as a dietary intervention for promoting health and combating diseases in adult population.
Methods: A comprehensive analysis of the latest clinical evidence is conducted. An electronic search was performed on trials using PubMed and Google Scholar as the main databases. Studies involving religious fasting, animal studies, studies conducted on neonates, infants, or children, were excluded.
Results: After reviewing 23 articles which discussed the IF in many health and disease domains, Intermittent fasting assumes a crucial role in promoting weight loss, managing diabetes, controlling blood pressure, offering potential benefits for individuals vulnerable to heart and liver diseases, and enhancing immune system in addition to potential positive impact on cancers.
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