The Prevalence of Antibiotic Misuse and its Associated Factors among Women of Reproductive Age in Jordan

المؤلفون

  • Hana Taha Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Omar AlHaddad Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Lujain Somrain Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Ahmad AL-SHAWABKA Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Khaled Alshaibe Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Layan AlDaher Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Nouf Alsharrah Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Jarallah Alajmi Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Alkawther Assad Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Ahmad Alathienat Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Osama Almemeh Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Najla alkamees Department of Family and Community Medicine, School of Medicine, The University of Jordan
  • Sireen Alkhaldi Department of Family and Community Medicine, Faculty of Medicine, University of Jordan, Amman, Jordan

DOI:

https://doi.org/10.35516/jmj.v59i5.4034

الكلمات المفتاحية:

Antibiotics، misuse، women، Jordan

الملخص

 

 الخلفية: يُعد سوء استخدام المضادات الحيوية تحديًا صحيًا عالميًا يُسرّع من مقاومة المضادات الحيوية ويهدد فعالية إدارة الأمراض. تهدف هذه الدراسة إلى تحديد مدى انتشار سوء استخدام المضادات الحيوية بين النساء الأردنيات في سن الإنجاب، بالإضافة إلى التعرف على العوامل الاجتماعية والديموغرافية المرتبطة بهذا السلوك.

المنهج والأجراءات: تم اعتماد نهج مقطعي، حيث استُخدمت استبيانات منظمة لجمع البيانات المتعلقة بالخصائص الاجتماعية والاقتصادية، وسلوكيات استخدام المضادات الحيوية، والعوامل المرتبطة بها. تم استقطاب 238 مشاركة، إلا أن 226 منهن استوفين معايير الأهلية.

النتائج: أشارت النتائج إلى أن معدل انتشار سوء استخدام المضادات الحيوية بين الفئة المستهدفة بلغ 25.7%، وأشارت النتائج الى وجود ارتباطات ضعيفة بينه وبين ارتفاع دخل الأسرة وحجم الأسرة الأكبر. من ناحية أخرى، لوحظ أن المستويات التعليمية الأعلى تقلل بشكل طفيف من احتمالية الحصول على المضادات الحيوية دون وصفة طبية. لم يتم تحديد أي ارتباطات ذات دلالة إحصائية بين المتغيرات الديموغرافية، مثل العمر أو التعليم أو الدخل، وسوء استخدام المضادات الحيوية.

الخلاصة: تسلط هذه النتائج الضوء على التفاعل المعقد بين العوامل الاجتماعية والاقتصادية وسوء استخدام المضادات الحيوية. يتطلب الحد من هذه السلوكيات، لا سيما بين الأسر ذات الدخل المرتفع والعائلات الكبيرة، تدخلات صحية عامة موجهة تركز على التوعية بالاستخدام الصحيح للمضادات الحيوية. تؤكد هذه الدراسة الحاجة إلى استراتيجيات شاملة للحد من سوء استخدام المضادات الحيوية، مما يساهم في تحسين النتائج الصحية على المستويين المحلي والعالمي ومكافحة مقاومة المضادات الحيوية.

المراجع

Beceiro A, Tomás M, Bou G. Antimicrobial resistance and virulence: A successful or deleterious association in the bacterial world? Clin Microbiol Rev. 2013;26(2):185–230.

Jonas OB, Irwin A, Berthe FC, Le Gall FG, Marquez PV. Drug-resistant infections: A threat to our economic future. Vol. 2. Washington, DC: World Bank Group; 2017.

Pulingam T, Parumasivam T, Gazzali AM, Sulaiman AM, Chee JY, Lakshmanan M, et al. Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome. Eur J Pharm Sci. 2022;170:106103.

Davey P, Pagliari C, Hayes A. The patient’s role in the spread and control of bacterial resistance to antibiotics. Clin Microbiol Infect. 2002;8 Suppl 1:43–68.

Sulis G, Daniels B, Kwan A, Gandra S, Daftary A, Das J, et al. Antibiotic overuse in the primary health care setting: A secondary data analysis of standardised patient studies from India, China and Kenya. BMJ Glob Health. 2020;5(9):e003393.

Abdelmalek S, AlEjielat R, Rayyan WA, Qinna N, Darwish D. Changes in public knowledge and perceptions about antibiotic use and resistance in Jordan: A cross-sectional eight-year comparative study. BMC Public Health. 2021;21(1):1.

Worldometer. Jordan population [Internet]. 2024 [cited 2025 Feb 19]. Available from: https://www.worldometers.info/world-population/jordan-population/

World Health Organization. WHO teams up with students and partners to increase community awareness about antimicrobial resistance [Internet]. [cited 2025 Feb 19]. Available from: https://www.emro.who.int/jor/jordan-news/who-teams-up-with-students-and-partners-to-increase-community-awareness-about-antimicrobial-resistance.html

Suaifan GA, Shehadeh M, Darwish DA, Al-Ijel H, Yousef AM, Darwish RM. A cross-sectional study on knowledge, attitude and behavior related to antibiotic use and resistance among medical and non-medical university students in Jordan. Afr J Pharm Pharmacol. 2012;6(10):763–70.

Haddadin RN, Alsous M, Wazaify M, Tahaineh L. Evaluation of antibiotic dispensing practice in community pharmacies in Jordan: A cross-sectional study. PLoS One. 2019;14(4):e0216115.

Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, et al. Antibiotic resistance—the need for global solutions. Lancet Infect Dis. 2013;13(12):1057–98.

Pereko DD, Lubbe MS, Essack SY. Public knowledge, attitudes and behaviour towards antibiotic usage in Windhoek, Namibia. South Afr J Infect Dis. 2015;30(4):27–9.

Epstein JB, Chong S, Le ND. A survey of antibiotic use in dentistry. J Am Dent Assoc. 2000;131(11):1600–9.

Murray CJ, Ikuta KS, Sharara F, Swetschinski L, Aguilar GR, Gray A, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629–55.

World Health Organization. The top 10 causes of death [Internet]. 2023 Nov 29 [cited 2025 Feb 23]. Available from: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death

Aljeldah MM. Antimicrobial resistance and its spread is a global threat. Antibiotics. 2022;11(8):1082.

O'Neill J. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Rev Antimicrob Resist. 2014.

Nusair MB, Al-Azzam S, Alhamad H, Momani MY. The prevalence and patterns of self-medication with antibiotics in Jordan: a community-based study. Int J Clin Pract. 2021;75(1):e13665.

Adanikin AI, Awoleke JO. Antenatal drug consumption: the burden of self-medication in a developing world setting. Trop Doct. 2017;47(3):193–7.

Creanga AA, Sabel JC, Ko JY, Wasserman CR, Shapiro-Mendoza CK, Taylor P, et al. Maternal drug use and its effect on neonates: a population-based study in Washington State. Obstet Gynecol. 2012;119(5):924–33.

Hallit S, Zahreddine L, Saleh N, Shakaroun S, Lahoud N. Practice of parents and pharmacists regarding antibiotics use in pediatrics: A 2017 cross-sectional study in Lebanese community pharmacies. J Eval Clin Pract. 2020;26(1):181–9.

Shehadeh M, Suaifan G, Darwish RM, Wazaify M, Zaru L, Alja’fari S. Knowledge, attitudes and behavior regarding antibiotics use and misuse among adults in the community of Jordan. A pilot study. Saudi Pharm J. 2012;20(2):125–33.

Ahmed KK. A review of antibiotic misuse and bacterial resistance in Iraq. East Mediterr Health J. 2024;30(10).

Almughais ES, Alreshidi FF, Ahmed HG. Prevalence of antibiotic misuse in cases of pneumonia and diarrhea in Saudi Arabia. Drug Target Insights. 2023;17:114.

Yusef D, Babaa AI, Bashaireh AZ, Al-Bawayeh HH, Al-Rijjal K, Nedal M, et al. Knowledge, practices and attitude toward antibiotics use and bacterial resistance in Jordan: A cross-sectional study. Infect Dis Health. 2018;23(1):33–40.

Almaaytah A, Mukattash TL, Hajaj J. Dispensing of non-prescribed antibiotics in Jordan. Patient Prefer Adherence. 2015;9:1389–95.

Muflih SM, Al-Azzam S, Karasneh RA, Conway BR, Aldeyab MA. Public health literacy, knowledge, and awareness regarding antibiotic use and antimicrobial resistance during the COVID-19 pandemic: A cross-sectional study. Antibiotics. 2021;10(9):1107.

Ayenew W, Tessema TA, Anagaw YK, Siraj EA, Zewdie S, Simegn W, et al. Prevalence and predictors of self-medication with antibiotics in Ethiopia: a systematic review and meta-analysis. Antimicrob Resist Infect Control. 2024;13(1):61.

Grigoryan L, Monnet DL, Haaijer-Ruskamp FM, Bonten MJ, Lundborg S, Verheij TJ. Self-medication with antibiotics in Europe: a case for action. Curr Drug Saf. 2010;5(4):329–32.

IBM Corp. IBM SPSS Statistics for Windows, Version 27.0. Armonk, NY: IBM Corp; 2020.

Sawair FA, Baqain ZH, Abu Karaky A, Abu Eid R. Assessment of self-medication of antibiotics in a Jordanian population. Med Princ Pract. 2009;18(1):21–5.

Mallah N, Orsini N, Figueiras A, Takkouche B. Income level and antibiotic misuse: a systematic review and dose–response meta-analysis. Eur J Health Econ. 2022;23(6):1015–35.

Abu Hammour K, Jalil MA, Al-Azzam SI, et al. Public Patterns and Determinants of Antibiotic Self-Medication and Antibiotic Knowledge in Southern Jordan. Antibiotics. 2024;13(1):98.

JAC-AMR. Self-medication with antibiotics: Patterns and drivers in low- and middle-income countries. J Antimicrob Chemother. 2023;78(4):785–93.

Sabuncu E, David J, Bernède-Bauduin C, et al. Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002–2007. PLoS Med. 2009;6(6):e1000084.

Roque F, Soares S, Breitenfeld L, Figueiras A, Herdeiro MT. Influence of community pharmacists’ attitudes on antibiotic dispensing behavior: a cross-sectional study in Portugal. Clin Ther. 2015;37(1):168–77.

Huttner B, Goossens H, Verheij T, Harbarth S. Characteristics and outcomes of public campaigns aimed at improving the use of antibiotics in outpatients in high-income countries. Lancet Infect Dis. 2010;10(1):17–31.

World Health Organization. Antimicrobial Resistance in the Eastern Mediterranean Region: Progress and Perspectives. Cairo: WHO EMRO; 2023.

McNulty CAM, Boyle P, Nichols T, Clappison P, Davey P. Don’t wear me out—the public’s knowledge of and attitudes to antibiotic use. J Antimicrob Chemother. 2007;59(4):727–38.

التنزيلات

منشور

2025-12-29

كيفية الاقتباس

Taha, H., AlHaddad, O. ., Somrain, L. . ., AL-SHAWABKA, A. ., Alshaibe , K. ., AlDaher , L. ., Alsharrah, N. ., Alajmi , J. ., Assad, A. ., Alathienat , A. ., Almemeh, O. ., alkamees, N. ., & Alkhaldi, S. . (2025). The Prevalence of Antibiotic Misuse and its Associated Factors among Women of Reproductive Age in Jordan. المجلة الطبية الأردنية, 59(5). https://doi.org/10.35516/jmj.v59i5.4034

إصدار

مجلد 59 عدد 5 (2025): Special Issue: Antimicrobial Resistance (AMR): Challenges and Opportunities

القسم

Special Issue: Antimicrobial Resistance (AMR): Challenges and Opportunities