التحقيق في فعالية بخاخ عشبي، Immuno Plus، في التخفيف من القرحة: رؤى من دراسة نموذج الفأر

المؤلفون

  • Yusuf Chimthanawala Mayons Pharmaceutical Pvt. Ltd. Nagpur 440026, Maharashtra, India
  • Nasreen Chimthanawala Mayons Pharmaceutical Pvt. Ltd. Nagpur 440026, Maharashtra, India
  • Shagufta Khan Institute of Pharmaceutical Education and Research,Wardha
  • Shilpa Padhare Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha 442001, Maharashtra, India
  • Ankit Kediya Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha 442001, Maharashtra, India

DOI:

https://doi.org/10.35516/jjps.v19i1.3454

الكلمات المفتاحية:

قرحة، كركمين، الإجهاد التأكسدي، أزاديراختا، تينوسبورا

الملخص

علاج القرحة القلاعية المتكررة (RAS) يمثل تحديًا. تم تقييم بخاخ Immuno Plus، الذي يحتوي على Aspidosperma (10% v/v)، Ocimum sanctum (20% v/v)، Curcuma longa (20% v/v)، Tinospora cardifolia (20% v/v)، Echinacea angustifolia (20% v/v)، وAzadirachta indica (10% v/v) لنشاطه المضاد للقرحة. تم تحفيز القرحة بحمض الأسيتيك في أربعة وخمسين فأرًا من نوع ويستار الألبينو تم تقسيمهم إلى تسع مجموعات. بدأ العلاج في اليوم الثالث، بمجرد أن تطورت القرحة بوضوح. مجموعة واحدة عملت كمجموعة تحكم ولم تتلق أي علاج، بينما تم علاج المجموعات الأخرى إما بمستخلصات فردية، أو Immuno Plus، أو تركيبة مسوقة. بحلول اليوم السابع، لا يزال لدى مجموعة التحكم ظهارة متقطعة، في حين لوحظت إعادة تكوين الظهارة والشفاء في المجموعات المعالجة بـ Immuno Plus والتركيبة المسوقة. كان هناك تقليل طفيف في حجم القرحة في المجموعات المعالجة بالمستخلصات الفردية بنفس الجرعة، مقارنةً بمجموعة Immuno Plus، التي تحتوي على مزيج من جميع المستخلصات. أظهر الرذاذ تأثيرات تآزرية، حيث عالج جوانب مختلفة من تكوين القرحة وشفائها.

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التنزيلات

منشور

2026-01-12

كيفية الاقتباس

Chimthanawala, Y., Chimthanawala, N., Khan, S., Padhare, S., & Kediya, A. (2026). التحقيق في فعالية بخاخ عشبي، Immuno Plus، في التخفيف من القرحة: رؤى من دراسة نموذج الفأر. Jordan Journal of Pharmaceutical Sciences, 19(1), 201–210. https://doi.org/10.35516/jjps.v19i1.3454

إصدار

القسم

Articles
##plugins.generic.dates.received## 2024-10-04
##plugins.generic.dates.accepted## 2025-01-16
##plugins.generic.dates.published## 2026-01-12

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