A Review on the Application of Electrospun Herbal Extract-Loaded Metallized Nanofiber Composites as Wound Healing Promoter: Fabrication, Efficacy, and Safety

Authors

  • Hebah Ayash Institute of Health Sciences, Department of Pharmaceutical Toxicology, Yeditepe University, Istanbul, Türkiye.
  • Muhammed Hamitoğlu Institute of Health Sciences, Department of Pharmaceutical Toxicology, Yeditepe University, Istanbul, Türkiye.
  • Soodabeh Davaran Department of Medicinal Chemistry, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Ahmet Aydin Institute of Health Sciences, Department of Pharmaceutical Toxicology, Yeditepe University, Istanbul, Türkiye.

DOI:

https://doi.org/10.35516/jjps.v18i2.2506

Keywords:

Nanofibers, electrospinning, Multimodal nanostructure, Wound healing

Abstract

Electrospinning is a promising technique for wound healing applications, as it enables the fabrication of nanostructures that closely mimic the natural extracellular matrix. This review highlights the potential of electrospun nanofiber composites loaded with herbal extracts and metal nanoparticles as effective wound healing agents. Herbal extracts, known for their antioxidant, anti-inflammatory, and antibacterial properties, contribute significantly to therapeutic outcomes. The incorporation of metal nanoparticles further enhances antimicrobial activity and accelerates the healing process. This review provides a comprehensive overview of the fabrication methods, efficacy, and safety of electrospun herbal extract-loaded metallized nanofiber composites in wound healing applications.

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2025-06-25

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Ayash, H. ., Hamitoğlu, M., Davaran, S. ., & Aydin, A. (2025). A Review on the Application of Electrospun Herbal Extract-Loaded Metallized Nanofiber Composites as Wound Healing Promoter: Fabrication, Efficacy, and Safety. Jordan Journal of Pharmaceutical Sciences, 18(2), 496–508. https://doi.org/10.35516/jjps.v18i2.2506

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